Blood Pressure Response Under Chronic Antihypertensive Drug Therapy
نویسندگان
چکیده
منابع مشابه
Antihypertensive Drug Therapy in Consideration of Circadian Blood Pressure Variation*
J-MUBA was a large-scale clinical study which, for the first time in the world, evaluated the effects of an antihypertensive drug on circadian BP variation in more than 600 patients with hypertension. Although ACE inhibitors reportedly exert equal 24-hour antihypertensive effects on daytime and nighttime BP, and -blockers are reported to have weaker effects on nighttime BP than on daytime BP. H...
متن کاملFrom 'optimal' to 'borderline' blood pressure in subjects under chronic antihypertensive therapy.
OBJECTIVES The ESH2003 report (J Hypertens 2003, 21:1011-1053) has classified brachial blood pressure into six groups reflecting the consistently increasing cardiovascular risk caused by high blood pressure. Chronically treated hypertensive individuals with well-controlled blood pressure retain higher cardiovascular risk than normotensive untreated individuals. Differences between these groups ...
متن کاملInfluence of albuminuria and glomerular filtration rate on blood pressure response to antihypertensive drug therapy
BACKGROUND Albuminuria and glomerular filtration rate (GFR), two factors linked to kidney and vascular function, may influence longitudinal blood pressure (BP) responses to complex antihypertensive drug regimens. METHODS We reviewed the clinic records of 459 patients with hypertension in an urban, academic practice. RESULTS Mean patient age was 57-years, 89% of patients were African America...
متن کاملBlood pressure response under chronic antihypertensive drug therapy: the role of aortic stiffness in the REASON (Preterax in Regression of Arterial Stiffness in a Controlled Double-Blind) study.
OBJECTIVES We sought to evaluate the role of arterial stiffness on blood pressure (BP) response to drug treatment. BACKGROUND Increased arterial stiffness (pulse wave velocity [PWV]) is associated with increased systolic blood pressure (SBP). Antihypertensive drug therapy achieves better control of diastolic blood pressure (DBP) than SBP does, implying that increased PWV might be a predictor ...
متن کاملGenetics of blood pressure, hypertensive complications, and antihypertensive drug responses.
Hypertension is the most prevalent, treatable risk factor for diseases of the heart, brain and kidneys. In this review, we discuss advances in understanding of the genetics of blood pressure regulation, the development of hypertensive complications and the pharmacodynamics of antihypertensive drug responses. Discovery of single gene mutations that cause hypertension or hypotension in humans sug...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2009
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2008.09.046